How we can hijack the media, in four easy lessons
Love it, hate it, good story, bad story... the media are going to keep reporting on ME/CFS no matter what. But isn’t it time that we saw that coverage as an opportunity?
Discuss the article on the Forums.

COMT CBS but not MTFHR! Any advice?

Discussion in 'Genetic Testing and SNPs' started by Al Klein, Jul 29, 2013.

  1. Al Klein

    Al Klein Senior Member

    Not what I was expecting, but here they are
     
  2. Valentijn

    Valentijn Activity Level: 3

    Messages:
    11,459
    Likes:
    27,973
    Can you show us the actual results? It can make a difference which CBS it is, and whether results are +/+ or +/-.
     
  3. Al Klein

    Al Klein Senior Member

    I can't seem to upload the picture on the iPad! Will try later
     
  4. Helen

    Helen Senior Member

    Messages:
    1,367
    Likes:
    1,782

    Any mutations in the MTR and/or MTRR genes?

    Helen
     
  5. Al Klein

    Al Klein Senior Member

    MTRR A 66G ++
     
  6. Al Klein

    Al Klein Senior Member

    MTRR A664A +-
     
  7. Al Klein

    Al Klein Senior Member

    This means I don't recycle b12 does this mean I don't use up stores from the liver and hence need a supply every day? I Am taking jarrows 5000 daily sublingually and seem ok-ish
     
  8. Helen

    Helen Senior Member

    Messages:
    1,367
    Likes:
    1,782
    I can´t say what happens in your liver, but your mutations indicate that you have an increased need for B12. Maybe you should have injections daily or every second day with methylcobalamin to get what you really need (my own and others experience with fewer mutations) . At least your mutation show that you, without b12 supplementation, might have a blocked methylation and lowered level of reduced glutathione as described by Rich Van Konynenburg.

    I read somewhere here that Jarrows isn´t longer as effective as before. People changed brand to ?. I think you should take some folate (you don´t need the bioactive ones as far as I can see) together with the B12 as they co-work. Best of luck!

    Helen
     

See more popular forum discussions.

Share This Page