Explanation/Validation If it suits you, by all means do it. Believe me, once the WPI work is replicated--and a positive test actually does provide an explanation/validation, I will be at the front of the line. Still, I just want to make it clear to everyone, that right now, a positive test for XMRV provides neither. A lot of us were down this road with Dr. Jose Montoya's work on HHV 6 in 2006-7. I had two separate tests done for HHV-6 (both negative). His larger study for replication purposes was essentially a bust. Please don't take this as pessimism. No one wants to see a causal relationship between XMRV and this illness proven more than I do. I just urge caution as someone who has been down the "this is it" road before.