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Combination of pregabalin with duloxetine for fibromyalgia: A randomized controlled trial

Discussion in 'Other Health News and Research' started by shannah, Mar 19, 2016.

  1. shannah

    shannah Senior Member

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    Out of Canada:

    Abstract


    Fibromyalgia is a syndrome characterized by chronic widespread pain and associated with sleep disturbance, depression, fatigue and cognitive dysfunction. Polypharmacy is commonly used but supportive evidence is limited. Most fibromyalgia trials focus primarily on pain reduction with monotherapy. This trial compares a pregabalin-duloxetine combination to each monotherapy.

    SUMMARY:

    This double-blind randomized controlled trial demonstrates improved outcomes with a pregabalin-duloxetine combination over either single drug for fibromyalgia.

    http://www.ncbi.nlm.nih.gov/pubmed/26982602
     
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  2. Sushi

    Sushi Moderation Resource Albuquerque

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    That's Lyrica and Cymbalta for those who don't know the generic names.
     
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  3. barbc56

    barbc56 Senior Member

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    Thanks @Sushi I was getting ready to look these up. Unfortunately, I can't take either one but would be interested if others have tried this.

    Interesting topic @shannah
     
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  4. panckage

    panckage Senior Member

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    Lyrica makes me brain dead and cymbalta makes me sleep for 20 hours a day. I guess being braindead and unconciious is one way to deal with pain :rofl:
     
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