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Columbia University is this new?

Discussion in 'XMRV Research and Replication Studies' started by joyscobby, Dec 25, 2009.

  1. joyscobby

    joyscobby Senior Member

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    http://jvi.asm.org/cgi/reprint/JVI.01969-09v1.pdf found this not sure if new or not. It does say that it is published ahead of print 16 December, 2009.

    I have not read it all either as very technical / medical but someone else maybe able to understand it.
     
  2. fresh_eyes

    fresh_eyes happy to be here

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    mountains of north carolina
    Hi joyscobby. It's news to me. From the conclusion:

    This study shows that XMRV is capable of replicating efficiently in LNCaP prostate cells and induces the release of high levels of virus. This may in part be due to an enhanced transcriptional environment within LNCaP cells that allows for production of more viral proteins and subsequent budding of viral particles. The increase in transcriptional activity of the XMRV LTR is totally attributable to the U3 region and requires a GRE sequence element within the U3. The data presented further indicate that XMRV transcription can be enhanced by steroids, suggesting that XMRV may show selectivity for hormone responsive cell types including the prostate.
     

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