I've just been prescribed co-codamol for inflammatory back pain associated with my ME which has got worse over the last few months (the pain, that is). I've just had an X-ray in case there is something else wrong so my doctor is clearly taking the pain seriously. The info leaflet in the packet warns that people can become dependent on co-codamol and this has scared me. Apparently it is an opiate! I don't want to get hooked and add to my problems. The pain is intermittent and somewhat debilitating but I could continue to survive without painkillers - I am already so disabled by fatigue that another hour or two lying down isn't going to make much difference to my lifestyle. The dose is two tablets containing 500mg of paracetomol and 8mg of codeine phosphate four times a day. I took the first dose 90 minutes ago and it has had zero effect on my back pain (but I now have a slight headache!). Any advice/experience? Are there any pain drugs that have good evidence behind them for being effective in ME that I should ask for instead?