The last month Idebenone has stopped working for me. I had no idea why and have been searching for answers. Prior to this month of hell, it helped immensely with energy levels and muscle function I have been looking on pubmed for info . So I guess now Idebenone is causing more superoxide why? For 18 months it worked tremendously, to the point I went to the gym. Then did too much crashed, a few days later lots of B12 caused apparent B2 deficiency; the results Idebenone does not work for me at all. How do I rectify this? Adding Coq10? Can somebody who understands this better than me speak on it? I would greatly appreciate.