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Clinical Trial Results of NeuroProtek in ASD

Discussion in 'Other Health News and Research' started by shannah, Aug 16, 2012.

  1. shannah

    shannah Senior Member

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    The clinical trial results on NeuroProtek are out on PubMed now.

    http://www.ncbi.nlm.nih.gov/m/pubmed/22697063/

    A case series of a luteolin formulation (NeuroProtek®) in children with autism spectrum disorders.Theoharides TC, Asadi S, Panagiotidou S.

    Int J Immunopathol Pharmacol. 2012 Apr-Jun;25(2):317-23.
    Affiliation

    Abstract

    There has been an impressive, little understood increase in cases of autism spectrum disorders (ASD). The lack of any distinctive pathogenetic mechanism has hampered the development of any effective treatments. Increasing evidence indicates oxidative stress, brain inflammation, gastrointestinal (GI) dysfunction and allergic symptoms may be present in ASD patients. The flavone luteolin has anti-oxidant, anti-flammatory, anti-allergy and neuroprotective properties. Given these findings, a dietary supplement was developed with a unique mixture of luteolin with the related flavonoids quercetin and rutin in a liposomal formulation of olive kernel oil (OKO), which increases their absorption. Results are presented for children with ASD (n=37, 4-14 years old) who had not obtained any benefit from multiple other regimens and who used this formulation for at least 4 months. GI and allergy symptoms improved in about 75 percent of children, eye contact and attention in 50 percent, social interaction in 25 percent and resumption of speech in about 10 percent. There were no adverse effects. Even though these results represent an uncontrolled open case series, they are encouraging because they suggest good tolerability and potential effectiveness.
    PMID

    22697063 [PubMed - indexed for MEDLINE]
  2. jeffrez

    jeffrez Senior Member

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    Sounds very good. I'm getting ready to try this stuff.
    katim likes this.
  3. nanonug

    nanonug Senior Member

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    Virginia, USA
  4. shannah

    shannah Senior Member

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    A testimonial on Neuroprotek from a child with Autism.

    "This child had many allergies, difficulty focusing and expressing himself before starting on NeuroProtek in November 2011. This short video was recorded before Dr. Theoharides lecture during Autism One on May 27, 2012 and is shown with the child's parents' permission."

    http://www.mastcellmaster.com/video-english-autism.html
  5. Aquila

    Aquila

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    This looks good but very expensive. 8 caps a day for average weight at 50p each is over 1000 pounds a year. Has anybody tried it?
  6. camas

    camas Senior Member

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    I'm giving it a two-month trial -- just six caps a day because of the cost. I've only taken it for four days, so don't have anything to report yet other than softer skin.
  7. nanonug

    nanonug Senior Member

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    I am currently taking 9 caps/day with additional quercetin. To me, it makes a significant difference, especially in the energy and brain fog departments.
    camas and katim like this.
  8. Aquila

    Aquila

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    I bought some of this and it actually seemed to make me worse. I do go up and down so I'll stick with it for a bit but I've read that people who are sensitive to salicylates are very sensitive to quercetin. I couldn't find much more about it though. I don't actally know whether I'm allergic to salicyates but I do know that if I go in a room which has a glass of red wine in it makes my sinuses swell up, my face go red and generally makes me feel rubbish which I've never understood.
  9. Sushi

    Sushi Moderator and Senior Member Albuquerque

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    Quercitin can also slow down the phase I detox--another possibility--to complicate the picture!

    Sushi
  10. natasa778

    natasa778 Senior Member

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    The latest version of Neuroprotek is supposed to have only a miniscule amount of quercertin in it. There is another product out there by another company that is lueolin-only I believe, Lutimax.
  11. Aquila

    Aquila

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    That's interested sushi and Natasa. I've read before that all Bioflavinoids are salicylates. Has anyone else had reactions to it? I actually rarely have any reaction to supplements.

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