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Clinical challenges in the diagnosis and management of POTS

Discussion in 'Other Health News and Research' started by Kati, Sep 25, 2016.

  1. Kati

    Kati Patient in training

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    Clinical challenges in the diagnosis and management of postural tachycardia syndrome

    Jones PK1, Shaw BH2, Raj SR3.

    Author information
    • 1Department of Neurology, UT Health Science Center San Antonio, San Antonio, Texas, USA.
    • 2Cumming School of Medicine, University of Calgary, Calgary, Canada.
    • 3Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, Cumming School of Medicine, University of Calgary.
    http://www.ncbi.nlm.nih.gov/pubmed/27660311

    Abstract

    Postural tachycardia syndrome (POTS) is a multifactorial clinical syndrome defined by an increase in heart rate of ≥30 bpm on standing from supine position (or ≥40 bpm in children).

    It is associated with symptoms of cerebral hypoperfusion that are worse when upright and improve when in supine position.

    Patients often have additional symptoms including severe fatigue and difficulty concentrating.

    There are several possible pathophysiologic mechanisms including hypovolaemia, small-fibre peripheral neuropathy and hyperadrenergic states.

    POTS can also be associated with several disorders including mastocytosis, Ehlers-Danlos syndrome (hypermobility type) and autoimmune disorders.

    The treatment is focused on symptom relief and not solely on reducing tachycardia.

    Given its varying presentations, it is important to employ a practical, mechanism-focused approach to the diagnosis and management of POTS.
     
    Last edited: Sep 25, 2016
    Mij, Sushi, ScottTriGuy and 1 other person like this.
  2. Sushi

    Sushi Senior Member Albuquerque

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    Now that's exciting news! :confused: When is someone going to come up with something new and useful in the management of POTS, and maybe even look upstream for causal factors?:( I know that there are some hypotheses that are interesting but basically POTS patients have been treated with the same "control symptom" protocols for ever and ever.
     
    Mel9 likes this.
  3. Kati

    Kati Patient in training

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    Dr Raj at University of Calgary, is one of the authors of this paper and is doing a study on auto-antibodies in POTS patients. I will be following his work
     
    mango and Mel9 like this.
  4. Sushi

    Sushi Senior Member Albuquerque

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    Now that would be interesting! Is this the same Dr. Raj who used to be at Vanderbilt?
     
  5. Denise

    Denise Senior Member

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    Yes. Same person. :)
     
  6. Kati

    Kati Patient in training

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    Yes, same one. Now in Calgary.
     
    Sushi likes this.
  7. OverTheHills

    OverTheHills

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    I can only see the abstract.
    Does anyone have access to the full text and can share some insights?
    Thankyou
    OTH
     

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