we usually have dysfunctional hormones that arent synched with our proper sleep cycles. So i think if one supplemented all these hormones(that one is low in) that are suppose to be high in the morning like cortisol, dhea and testosterone etc etc in the morning when they should be high and possibly bromocriptine which can help reset the body clock. then at night phos serine or some other cortisol blocker at night with melatonin and sleep meds?? can help turn our body clock back to close to normal. This seems to have helped me but it aint perfect. I do seem to be sleeping better then i was. I also havent done any actual night shifts for over 2 years, i finish at either 6pm or 11pm which has been a good help. If i was forced to do night shifts then i would have to push the cfs/me immune dysfunction card which i have kept from my employee so far, then see what happens. For some of us i just dont think melatonin on its own is enough, we need to try and control our other hormones to sync our body clocks??