New Atmosphere, New Vision: Gibson and Whittemore Kick Off Invest in ME Conference 2016
Mark Berry reports on Dr. Gibson's introduction and Dr. Whittemore's keynote speech, at the 11th Invest in ME International ME Conference in London.
Discuss the article on the Forums.

Chronic fatigue syndrome is in your gut, not your head

Discussion in 'Latest ME/CFS Research' started by Gloria H, Jul 5, 2016.

Thread Status:
Not open for further replies.
  1. Gloria H

    Gloria H

    Messages:
    79
    Likes:
    25
    South Dakota
    https://www.sciencedaily.com/releases/2016/06/160627160939.htm

    Now, for the first time, Cornell University researchers report they have identified biological markers of the disease in gut bacteria and inflammatory microbial agents in the blood.

    In a study published June 23 in the journal Microbiome, the team describes how they correctly diagnosed myalgic encephalomyeletis/chronic fatigue syndrome (ME/CFS) in 83 percent of patients through stool samples and blood work, offering a noninvasive diagnosis and a step toward understanding the cause of the disease.
     
    JaimeS and Justin30 like this.
  2. alex3619

    alex3619 Senior Member

    Messages:
    12,493
    Likes:
    35,122
    Logan, Queensland, Australia
    Its not the first time. It also does not prove its causal. It does strongly demonstrate something is wrong that is deserving of more research funding so we can find out the rest.

    Is this the second thread on this?
     
    JaimeS, Ben H, Justin30 and 1 other person like this.
  3. Thinktank

    Thinktank Senior Member

    Messages:
    1,239
    Likes:
    1,396
    Europe + Asia
  4. kangaSue

    kangaSue Senior Member

    Messages:
    838
    Likes:
    913
    Brisbane, Australia
    Valentijn and alex3619 like this.
  5. perrier

    perrier Senior Member

    Messages:
    515
    Likes:
    891
    Diet and probiotics can't solve this nightmare, me thinks. If only....all the suffering would be replacing by swimming, running, hiking, working, marrying, procreating, etc.
     
    actup likes this.
  6. EtherSpin

    EtherSpin Senior Member

    Messages:
    172
    Likes:
    226
    Melbourne , Australia
    Im down for whatever helps the most dramatically,quickly or for the longest period,right now that seems to be drugs like Ritux followed by antivirals - what are the success rates in studies with the gut? I've not seen much but I can't read well! my docs are all for the gut and say the ritux bit is very preliminary but thats not my take on the situation ... and I would like to do antivirals but no doc round here is into that and the meds aren't subsidised
     
  7. kangaSue

    kangaSue Senior Member

    Messages:
    838
    Likes:
    913
    Brisbane, Australia
    Fecal transplant should be a faster quick fix than probiotics, you get a whole new microbiome in the one hit. Now, if they could only explain why it doesn't work for everyone.......
     
  8. Justin30

    Justin30 Senior Member

    Messages:
    1,065
    Likes:
    1,280
    Possibly due to the damage done to the Gut by the initial insult which causes a dybiosis, leaky gut and pemeability issues.

    If the epithial layer of the gut ishighly damaged then fecal transplants may just translicate and lead to the perpetuating cycle of LPS in the serum ie. Neuro and endotoxins.

    These toxins perpetuate immune dysregulation and autoimmunity most likley.
     
  9. EtherSpin

    EtherSpin Senior Member

    Messages:
    172
    Likes:
    226
    Melbourne , Australia
    it would be interesting to monitor the gut (in whatever fashion is possible!) after B-cell treatments and as I harp on about in every thread possible, it would be great to see CFS treatment centres where blood filtration for waste products (of broken energy cycles, if this is something possible) happens in tandem with depletion of errant B-cells and faecal transplants if samples have shown flora is still very strangely made up.
    Peptides should also be given especially if the recovering patient is engaging in mild exercise. folistatin for instance would ensure that if the patient has long rest periods of days between overt exercise sessions muscle will be retained and just build and build instead of atrophy occuring
     
    Justin30 likes this.
  10. kangaSue

    kangaSue Senior Member

    Messages:
    838
    Likes:
    913
    Brisbane, Australia
    Yeah, that was my take on it too but then it doesn't explain why some people with Crohn's and Ulcerative Colitis can get remission using FMT when the disease in both cases causes severe mucosal injury which should be resulting in intestinal permeability for the whole cohort.
     
    Justin30 likes this.
  11. Kina

    Kina

    Messages:
    10,131
    Likes:
    17,218
    Sofa, UK
Thread Status:
Not open for further replies.

See more popular forum discussions.

Share This Page