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Nitric oxide and its possible implication in ME/CFS (Part 1 of 2)
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Chronic fatigue syndrome - A neuroimmunological model (Arnett et al., 2011)

Discussion in 'Latest ME/CFS Research' started by Dolphin, May 29, 2011.

  1. Dolphin

    Dolphin Senior Member

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    I just read this. It's a hypothesis paper so no new data although it does draw together some data from CFS and other areas (which might be new to people) e.g. anti-TNF drugs have been tried in Alzheimers' Disease

     
  2. Dolphin

    Dolphin Senior Member

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    Section on graduated exercise therapy (GET)

    It has a section on graduated exercise therapy (GET).

    Nothing definitive but I know lots of people are interested in mentions of it:

     
  3. Snow Leopard

    Snow Leopard Senior Member

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    That "Dangerous exercise" article looks interesting. ;)
     
  4. WillowJ

    WillowJ Senior Member

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    Do you have any author/journal info on this?
     
  5. Enid

    Enid Senior Member

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    A quick response before reading in full Dolphin - it is good to see some serious hypothesising now.
     
  6. Snow Leopard

    Snow Leopard Senior Member

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  7. WillowJ

    WillowJ Senior Member

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  8. Francelle

    Francelle Senior Member

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    I like the sound of this, from what I have read!

    Does anyone know if the full text article has yet been published as this abstract in April was 'Epub ahead of print'? (This is a different question than, which author and publication which has already been asked).
     
  9. Dolphin

    Dolphin Senior Member

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    It can be consideded as published from when it was made available as a full article i.e. can be quoted already. I have no idea when it might be in a print edition.
     
  10. Firestormm

    Firestormm Guest

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  11. Marco

    Marco Old blackguard

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    Sounds plausible and certainly ties in with my own subjective feelings of brain inflammation and with Maes' gut permeability leading to inflammation paper.

    As the paper points out, inhibiting TNF alpha may not be a good thing with a dysfunctional immune system or if there is persistent infection.

    There are a range of natural TNF alpha inhibitors :

    http://www.life-enhancement.com/article_template.asp?id=2428

    I tend to use curcumin.

    Given the above caveats it might be best to try a compound that inhibits TNF alpha plus has an anti-viral action.
     
  12. Guido den Broeder

    Guido den Broeder *****

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    Rotterdam, The Netherlands

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