Hi
@ChrisArmstrong thanks so much for a great webinar and for being so helpful with questions.
I will just highlight something
@Mark noted about a talk Jo Cambridge gave at the RME Sweden conference just a day or so ago on the other thread. Jo's talk was really good and included some new information regarding B cell behaviour. I don't know if you may have time to check out her talk.
Geraldine (Jo) Cambridge's lecture Rituximab for ME/CFS: Revealing immunological cues to underlying disease mechanisms starts at 02.53
https://play.vll.se/category/5/video/214/rme-konferens-19-october-2016-2
Mark said:
"Swedish conference thread, Jo Cambridge reports they are now finding elevated glycolysis in naive B cells of ME patients, working this up now:
http://forums.phoenixrising.me/inde...ilable-for-streaming.47449/page-3#post-776570
Could this hook up with the finding of non-mitochondrial excess ATP?"
She also noted other things about B cells that were interesting I can't pull out of my memory. Ill try and find them in her talk but someone may recall them better than me right now.
@ChrisArmstrong EDIT I just took another look at Jo's talk she said (in summary):
Changes in B cells in both naïve and memory B cell subsets compared to healthy controls.
Mitochondrial function.
- energy production/supply of key metabolites
- ? mitochondria not able to 'recover' from stress in ME/CFS?
Found differences in the way naïve B cells use energy compared to memory B cells and differences in resting B cells. They are writing all this up right now.
Somehow I missed the bit that Mark noted which is also really interesting. I wonder if you have thoughts about how all this might fit together.