Not sure if I agree with this at all -- but still found it pretty suprising... "“The problem we observed was that a lot of people with that SNP who we gave folapro to, which should help them, looked worse in the end. And the idea there is that there’s a reason to be methylation blocked. And so if you successfully unblock the methylation cycle, which you can do easier with folapro, if you have that SNP, is force you to make less glutathione, ergo the mindless attempt to unblock the methylation cycle, without realizing that the methylation block is essential to make glutathione is a mistake, and all that the SNP did was magnify your mistake." http://nopostergirl.com/2013/06/16/the-post-appointment-post-part-ii/ ???