I am looking only at the section of the GWS treatment guide that says it addresses CFS. It begins on page 97. I was not able to do the entire section. I only picked two things out of the treatment section that I know the most about. Graded exercise: They recommend graded exercise. And to support this, they reference three web sites that offer no citations to back up their claims. The IOM also cites two journal articles. The first is called The Neuroendocrinology of Chronic Fatigue Syndrome. It says nothing about graded exercise helping CFS patients. The second paper, called Endorphins and Exercise, doesn’t even deal with CFS. The IOM panel also fails to mention the studies that show negative effects from exercise. Pharmaceuticals: They only mention pain control and sleep. In contrast, the Canadian Consensus document includes a section on pharmaceuticals for a much wider range of symptoms. I also know of two books that cover a wide range of pharmaceuticals along with citations. I've seen better work from high school students. Here's what the IOM says about their review process. I added the bold lettering above. What this means is they accept no responsibility for the final product.