I was also wondering do most of CFIDS have "low immunity functioning" Or "chronically activated immunity" ? I know the question is more complex but overall I have read it can be both but there must be sub categories. People with chronic activated immunity must have some different symptoms or ways to diagnose and treat? I have not found too much information on this subject in detail besides an article ironically on same site for CFS Treatment Guidelines where I found the work by Dr. Goldsteins work on EBV treatment and of course his many other methods of treating various symptoms of CFIDS Any insight or direction to articles or research appreciated ! Thank you!