The CDC can't find CFS much less XMRV. The CDC studies "chronic unwellness" not CFS. They plan to analyze their findings in 2011. Here are their criteria for the Bibb county registry. http://www.fatigueregistry.org/sites/fatigueregistry/default.aspx?pid=678#28 • Current severe fatigue persisiting for one month or longer • One of the following for at least one month: - Unrefreshing sleep, - Problems with memory or concentration, or - Unexplained joint or muscle pain in the lower extremities • Age: 12 to 59, inclusive • Body mass index (BMI) les than 40.0 Here is a description of the Canadian Criteria: http://www.cfids-cab.org/MESA/ccpc.html The Canadian Expert Consensus Panel has published a medical milestone, the first clinical case definition for the disease known as myalgic encephalomyelitis/chronic fatigue syndrome. This definition is clearly a vast improvement over the CDC's 1994 Fukuda criteria, which led to misunderstanding in both research and treatment modalities by making "fatigue" a compulsory symptom but by downplaying or making optional the disease's hallmark of post-exertional sickness and other cardinal ME/CFS symptoms. In sharp contrast to the Fukuda criteria, this new clinical case definition makes it compulsory that in order to be diagnosed with ME/CFS, a patient must become symptomatically ill after exertion and must also have neurological, neurocognitive, neuroendocrine, dysautonomic, and immune manifestations. In short, symptoms other than fatigue must be present for a patient to meet the criteria. This case definition, which incorporates some of the current research on dysautonomia, cardiac, and immune problems, was published in the Journal of Chronic Fatigue Syndrome, Vol. 11 (1) 2003. It is summarized as follows: 1. POST-EXERTIONAL MALAISE AND FATIGUE: There is a loss of physical and mental stamina, rapid muscular and cognitive fatigability, post-exertional fatigue, malaise and/or pain, and a tendency for other symptoms to worsen. A pathologically slow recovery period (it takes more than 24 hours to recover). Symptoms exacerbated by stress of any kind. Patient must have a marked degree of new onset, unexplained, persistent, or recurrent physical and mental fatigue that substantially reduces activity level. 2. SLEEP DISORDER: Unrefreshing sleep or poor sleep quality; rhythm disturbance. 3. PAIN: Arthralgia and/or myalgia without clinical evidence of inflammatory responses of joint swelling or redness. Pain can be experienced in the muscles, joints, or neck and is sometimes migratory in nature. Often, there are significant headaches of new type, pattern, or severity. [Editor’s note: neuropathy pain is a common symptom and should be added here as well.] 4. NEUROLOGICAL/COGNITIVE MANIFESTATIONS: Two or more of the following difficulties should be present: confusion, impairment of concentration and short-term memory consolidation, difficulty with information processing, categorizing, and word retrieval, intermittent dyslexia, perceptual/sensory disturbances, disorientation, and ataxia. There may be overload phenomena: informational, cognitive, and sensory overload -- e.g., photophobia and hypersensitivity to noise -- and/or emotional overload which may lead to relapses and/or anxiety. 5. AT LEAST ONE SYMPTOM OUT OF TWO OF THE FOLLOWING CATEGORIES: AUTONOMIC MANIFESTATIONS: Orthostatic Intolerance: e.g., neurally mediated hypotension (NMH), postural orthostatic tachycardia syndrome (POTS), delayed postural hypotension, vertigo, light-headedness, extreme pallor, intestinal or bladder disturbances with or without irritable bowel syndrome (IBS) or bladder dysfunction, palpitations with or without cardiac arrhythmia, vasomotor instability, and respiratory irregularities. NEUROENDOCRINE MANIFESTATIONS: loss of thermostatic stability, heat/cold intolerance, anorexia or abnormal appetite, marked weight change, hypoglycemia, loss of adaptability and tolerance for stress, worsening of symptoms with stress and slow recovery, and emotional lability. IMMUNE MANIFESTATIONS: tender lymph nodes, sore throat, flu-like symptoms, general malaise, development of new allergies or changes in status of old ones, and hypersensitivity to medications and/or chemicals. 6. The illness persists for at least 6 months. It usually has an acute onset, but onset also may be gradual. Preliminary diagnosis may be possible earlier. The disturbances generally form symptom clusters that are often unique to a particular patient. The manifestations may fluctuate and change over time. Symptoms exacerbate with exertion or stress. This summary is paraphrased from Dr. Kenny van DeMeirleir's book Chronic Fatigue Syndrome: A Biological Approach, February 2002, CRC Press, pg. 275. The CDC Bibb county register does rule out: Bibb County does rule out: • Pregnancy within past 12 months • Stroke with no full recovery • Parkinson’s disease • Chronic obstructive pulmonary disease (COPD) or congestive heart failure • Insulin-dependent diabetes • Uncontrolled diabetes type II (HgbA1c < 9%) • Anemia • Uncontrolled hypo- or hyper-thyroidism • Uncontrolled hypertension (BP > 140/90) • Sickle cell anemia • Cancer within 5 years (except basal skin or currentl receiving chemotherapy • Untreated depression • Substance abuse problems within the past 2 years • Anorexia nervosa or bulimia nervosa within the past 5 years • Schizophrenia, bipolar I or II, or dementia • Hepatitis B or C All providers should complete a medical history.