MikeJackmin
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“Flowers” in the blood: A novel paired erythrocyte arrangement in a patient with chronic fatigue syndrome following infectious mononucleosis
Carrie E Burdzinski
PDF:
www.ijcasereportsandimages.com/archive/provisional_articles/2014-08/06_Z01_2014050070_CR_prov.pdf
Carrie E Burdzinski
PDF:
www.ijcasereportsandimages.com/archive/provisional_articles/2014-08/06_Z01_2014050070_CR_prov.pdf
"A 28-year-old caucasian female presented with chronic fatigue persisting for nine months following infectious mononucleosis. Laboratory evaluation excluded classic causes of fatigue. Peripheral blood smear examination revealed numerous pairs of unusual nondiscocytic c-shaped erythrocytes, coupled in perpendicular crosses resembling four-petalled flowers. the presence of the erythrocyte pairs abated with the patient’s recovery from chronic fatigue syndrome over a 24-month period. this erythrocyte arrangement has not been reported elsewhere in medical literature.
Conclusion: A novel erythrocyte “flower” formation was identified in a patient with chronic fatigue syndrome. the presence of this arrangement paralleled the course of the illness and was no longer observed upon recovery. the physiological relevance of the structure remains a subject for future research. several hypotheses are suggested, including enhanced membrane deformability resulting from elevated catecholamine levels, and immune-mediated agglutination, possibly stemming from viral infection."
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