Apply Biopsychosocial BPS abuse model to GWI (PTSD), which Dr. Nancy Klimas parallels with CFS and you get a reasonable basis for examining non-viral CFS causation. (“You live with constantly heightened cortisol levels. this has its effects on first gut, the immunesystem and so on. these are simple facts. That's the Bio part of BioPsychoSocial.” - @Sundancer, PR, 2/2/18.) GWI fits the BPS abuse model, accelerated. IOW, look at the symptoms of BPS abuse over time and you indeed get similar symptoms to the otherwise accelerated symptoms of GWI and CFS. I’m curious if Dr. Klimas has thought along these lines in modeling her GWI and CFS similarities? It certainly seems to take the viral component out of the equation (which hasn’t solved anything as yet) and focuses on the immune system gone awry, ergo the HPA axis dysfunction.