That's a good point to watch out for the rebalancing. We got back the 3rd nutraEval since starting treatment and his folate and potassium were both still low even tho he's on so much folate, b12, and b6. Oh and potassium but apparently not enough. That could be a reason for the highs and lows. I also don't have him on biotin. I had taken him off the b complex after the hives (not flush) reaction to increasing niacin and hadn't started trying to titrate the other b vitamins individually.