Has anyone tried a capsaicin cream or patch for ME/CFS pain? An abstract for a study located here states: The transient receptor potential vanilloid type 1 (TRPV1) is interesting, because according to wikipedia, the function of TRPV1 "is detection and regulation of body temperature. Additionally, TRPV1 provides sensation of scalding heat and pain (nociception)" as well as triggering a response that causes hypersensitivity to painful stimuli and the sensation of pain from non-painful stimuli. TRPV1 can be desensitized by overstimulating it with capsaicin, possibly for months at a time from a single topical application of the higher potency stuff, thereby providing pain relief in muscles. It looks like there's been successful trials of it for shingles, rheumatoid arthritis, and maybe fibromyalgia, though I haven't tried to read any of them yet. So has anyone tried the lower dose OTC capsaicin creams or patches and had any results? I just found one today at my local Dutch drug store, and I've currently got warm red swollen patches on my arms from trying it. But it sounds like it can take several weeks to get results.