About a month ago I read about Freddd's protocol and decided to try it, hoping it would solve the mitochondrial part of my problem. But I'm having a problem even starting with vitamin B complex. I tossed out my multivitamin (it contained folic acid) and replaced it with Douglas Laboratories B-Complex. I intended to take 1/2 capsule per day which would be 200mcg of folate, 25mg of B1, 10mg ob B2, 25mg of B3, 10mg of B6, 250mcg of mB12, 150mcg of biotin, 25mg of B5, 10mg of Intrinsic Factor. The first time I took only half of this (1/4 of the capsule) and had severe cramps, diarrhea and nausea. I felt so ill that I called my sister to come over just in case I passed out (I live alone). After a week I tried taking just 1/10th of the capsule each day. It was OK for a few days, but then I got the cramps and diarrhea again, though the pain was not as nauseating as the first time. Any ideas what could be causing this or how to proceed? I never took folate or Intrinsic Factor before. I have taken the rest before without problems, though most of them in lesser dosages.