Phoenix Rising tells QMUL: release the PACE trial data
Mark Berry, Acting CEO of Phoenix Rising, presents the Board of Directors’ open letter to Queen Mary University of London (QMUL) urging them to release the PACE trial data, and hopes that other non-UK organisations will join British charities in the same request...
Discuss the article on the Forums.

Can taking b vitamins without niacin cause niacin deficiency?

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by jwat87, Jan 27, 2015.

  1. jwat87

    jwat87

    Messages:
    28
    Likes:
    8
    If you take every b vitamin, SAM-E, TMG, without niacin, can this cause a niacin deficiency?
    Is it a good idea to take a small amount of niacin with everything else, even though it contributes to soaking up SAM-E?
     
  2. Gondwanaland

    Gondwanaland Senior Member

    Messages:
    4,444
    Likes:
    3,407
    Yes
    It will only be detrimental to methylation when it is in excess. AFAIK it should be taken proportionally to other Bs. Be sure to take the co-factors as well like magnesium, zinc, potassium.
     
  3. jwat87

    jwat87

    Messages:
    28
    Likes:
    8
    Can you tell me if this is a good ratio of b vitamins? This is what is found in the "swanson's activated bcomplex" that I have. I take one of these with an extra 1mg methylb12 (sublingual) tab. Is there a consensus on the correct ratios?

    Thiamin (vitamin B-1) (as benfotiamine)25 mg
    Riboflavin (as riboflavin 5'-phosphate)25 mg
    Niacin (as inositol hexanicotinate)50 mg
    Vitamin B-6 (as pyridoxal 5-phosphate)25 mg
    Folate(as Quatrefolic® [6S]-5-Methyltetrahydrofolic acid) 400 mcg100
    Vitamin B-12 (as methylcobalamin)250 mcg
    Biotin25 mcg
    Choline (as choline dihydrogen citrate)25 mg
    PABA (para-aminobenzoic acid)25 mg
    Pantethine (coenzyme A precursor)(from Pantesin® 55% pantethine)25 mg
    Inositol (from inositol hexanicotinate)12.5 mg
     
    sheclimber likes this.
  4. Gondwanaland

    Gondwanaland Senior Member

    Messages:
    4,444
    Likes:
    3,407
    I think it's different for everyone. If you have read Freddd's recommendations, he says to keep B1, B2 and B3 below 50mg, preferably around 30mg, and most folks here tend to agree with that.
    No.

    I have the same supplement at home and many people here like it. But it does not contain a free form of niacin
    http://en.wikipedia.org/wiki/Niacin#Inositol_hexanicotinate
    This sounds excellent to me if you tolerate it. Are you feeling better or worse on it?
     
  5. jwat87

    jwat87

    Messages:
    28
    Likes:
    8
    I feel better on it, but I haven't been taking it every day. Combined with SAM-E and TMG, even better.

    TMG seems to help with high heartrate and constant thirst feeling that I get sometimes, almost like a hypertension feeling. I'm not sure what causes it, but it seems methylation related. Could this be high homocysteine?
     
  6. Gondwanaland

    Gondwanaland Senior Member

    Messages:
    4,444
    Likes:
    3,407
    Take the way that makes you feel best.
    Check your urine pH, it sounds like high acidity to me. Could also be hyperthyroid (a little more B1 would help). Could be electrolyte imbalance (magnesium and potassium would help).
     
  7. jwat87

    jwat87

    Messages:
    28
    Likes:
    8
    I used a PH strip on my urine, it was neutral. Everything came back normal on the thyroid test. I feel much better after taking b vitamins, I'm guessing it has to do with folate deficiency (I have the double mutation for converting folate).
     
  8. Gondwanaland

    Gondwanaland Senior Member

    Messages:
    4,444
    Likes:
    3,407
  9. Sherpa

    Sherpa Ex-workaholic adrenaline junkie

    Messages:
    625
    Likes:
    774
    USA
    I think it's pretty good ratios and comprehensive formula. There is some debate as to whether coenzyme forms of B vitamins, as found in this formula, are "better" than standard ones... But I find they work OK. However I think methylfolate can be quite strong for some sensitive people so I like to take it separately... So that it can be skipped on some days, dose adjusted, etc.
     
  10. jwat87

    jwat87

    Messages:
    28
    Likes:
    8
    That is the only b complex I could find with p5p, methlyb12, methyfolate, and under 30mg doses of everything else. If you guys know of other bcomplex supps that are similar please post their brand names (they don't need to include folate or b12).
     
  11. Sherpa

    Sherpa Ex-workaholic adrenaline junkie

    Messages:
    625
    Likes:
    774
    USA
    Two that are 'pretty good' but not perfect are Nature Made B Complex with C ... And Seeking Health B-Minus

    For a multivitamin with everything consider Doctor's Best Multiple
     
  12. whodathunkit

    whodathunkit Senior Member

    Messages:
    1,158
    Likes:
    1,469
    I think it depends on what your diet is as to whether or not you will become unbalanced. I can't seem to take any form of supplemental niacin at all (even in a B complex) without having problems, thus always take my B's individually (separate pill for B2, separate pill for B6, etc.). Never any niacin, and I do fine. But then I drink milk and eat some whole wheat and other grains which probably helps me get enough niacin, and I know a lot of people here can't have milk or grains.

    FWIW, I needed some supplemental B's (but again, not niacin) when I first started doing methylation, even with my milk and grain consumption. But now things are relatively stable for me so don't really need to take them any more. Most days I don't take B's except mB12 injections.

    My take: if you're worried about niacin shutting down methylation, experiment a little bit. You should be able to know if it affects you adversely or not. If it does, and you eat a B-vitamin rich diet, you should be fine skipping it.
     
  13. sheclimber

    sheclimber

    Messages:
    38
    Likes:
    26
    Chicago, IL
    I just made the mistake of taking this one on an empty stomach - hello niacin flush! Lucky I knew what was happening otherwise I would have been terrified. My new plan is to take my last MeB12 and Folate dose with dinner and have the B-minus before bed with a little snack.
     
  14. jwat87

    jwat87

    Messages:
    28
    Likes:
    8
    Why does that one have so much niacin in it? 180mg seems like way too much.
     
  15. jwat87

    jwat87

    Messages:
    28
    Likes:
    8
    Does taking everything with niacin make you tired? I've actually been feely drowsy, I'm not sure if it's too much mb12 or the niacin.
     
  16. sheclimber

    sheclimber

    Messages:
    38
    Likes:
    26
    Chicago, IL
    I don't know it seems strange to me too, but I thought I'd try it since the Pure Encapsulations B-complex seemed to be boosting my need for folate. The B-Minus at night with food still causes a little flushing, so I'm assuming that's going to shut down methylation, which is clearly the opposite of what I'm going for. I am, however, trying to minimize the number of supplements I have to buy, but I may have to break down and do the Bs separately. NatureMade is my next experiment.
     

See more popular forum discussions.

Share This Page