Can someone help with 23andme data?

[Oci]

And the rare SNP program just got updated to include gene names, missense mutations, and pathogenic status. You can download the main program at https://sourceforge.net/projects/analyzemygenes/ and the ten_percent.zip and remarks.zip files to get the extra data, if you put them in the same directory with the other files for the program.

Well, I somehow messed up on this. I got the message
"This trial version is limited to 5MB per conversion.
For unlimited PDF conversions, upgrade to PDF Pronto Pro."
So, I paid my $9.99 assuming that the 23andme was over the 5 MB but now don't see any sign of the license code required.
Sorry to bother you but would appreciate any help you may have.

 

[Valentijn]

"This trial version is limited to 5MB per conversion.
For unlimited PDF conversions, upgrade to PDF Pronto Pro."

There's no license code for the program, and it doesn't require anything involving pdf conversions. Just download the files, unzip to the same directory, and run the Genes.Jar file. The results can be saved as a basic .pdf file (no converting involved), but saving it as a .txt (text) file is probably more useful.

 

[Flo]

Hello everyone,

I am very new to all this, and despite all the reading that I've done over the past weeks on this forum and others, I'm having a hard time understanding what my results/mutations mean, and what steps I should follow to address these mutations/how to start supplementing...

I'm a 32 y.o female, and I have a 9 month old.

My 23andme data (via Genetic Genie) is as follows (also attached):


For general health while I continue nursing, I'm supplementing with:

-Thorne Basic Nutrients 3 - https://www.thorne.com/products/oncology-support/dp/basic-nutrients-iii-without-copper-and-iron

-Viva Labs Krill Oil - http://vivalabs.com/products/krill-oil

-Jarrow Formulas Pterostilbene - http://www.jarrow.com/product/564/Pterostilbene

-Pure Encapsulations Magensium Glycinate (only at night) - http://www.pureencapsulations.com/magnesium-glycinate.html

I hope some of you can help me, I want to be healthy for my son.

-R

ps @Valentijn @caledonia @Freddd

you all are incredibly knowledgeable, and hoping maybe you could have a look at this, or point me in the right direction... Very grateful for your time and for what you guys are doing for so many members of this forum

I have been studying on how high dose cofactor vitamins can help some of these enzymes speed up if they have SNPs that lead to slower functioning enzyme. Take the MTHFR C677T SNP for example (you do not have this). It uses FAD as a cofactor which comes from riboflavin. There seem to be several studies that show higher doses of riboflavin can speed up these enzymes:
http://circ.ahajournals.org/content/113/1/74.short
http://www.clinchem.org/content/49/2/295.short

You do have the MTRR A66G SNP though, and MTRR uses FAD as well as FMN, both forms of reduced riboflavin. And research points to riboflavin speeding it us as well.
http://link.springer.com/article/10.1007/s12263-014-0435-1

You also have that MAOA R297R SNP

So I was thinking, maybe people with MTHFR C677T SNPs and MTRR A66G SNPs need more riboflavin than people with just MTHFR C677T SNPs?