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Can food cause disruption to methylation cycle

Hi
I am in the early stages of learning about methylation, me, cfs etc

I have ordered the 23.me test but I have sever reactions of anxiety when taking any Kind of vitamins. As I am folate deficient and anaemic I had a veg smoothie yesterday am desperate to feel well and though this would help . The smoothie consisted of 4 apples celery and cucumber and approx 6 Brazil nuts I have never ate them before . Then last night anxiety hit me and I haven't slept as I was having vivid thoughts. Is this coincidence or could this of triggered the anxiety off ?

Thanks
Lisa x