Hi folks, Caffine. Something I'm very aware of. Long story. Last year I worked, had to quit caffine completely because it just made me so fatigued, anxious, spaced out etc. It took many months to realize the benefit from quitting. I later found out when trying methylation, one cup of caffine could throw off my methtylation for days. If I drank caffine for a month or so, it could take weeks to get methylation going again. In my case, I suspect caffine causes excitoxicity and this results in some mild but cumulative nerve damage or something. I'm also wondering if affects uptake of certain nutrients? Stuff is addicting too. Makes it hard to quit. I forgot to vote on PEM. I do have post exertional malaise. i put down I can't touch the caffine, but I do anyway and pay for it.