I was just diagnosed with C. pneumoniae and prescribed clarithromycin ER for a relatively long duration. I have not taken antibacterials long-term before, so I'm asking this vast pool of knowledge we have here at PR for some advice/guidance. Is there anything in particular I should be aware of with long-term antibacterials? I remember hearing that there are problems with destroying gut bacteria. If I took probiotics, wouldn't they just get killed off by the antibacterial? Or is that a matter of the type of antibacterial? Has anyone hear taken clarithromycin ER? I've read about doxycycline and azithromycin for use in cpn, but I haven't heard much about clarithromycin.