My leg muscles have always been a big problem area for me, and it's usually from exertion of these muscles that causes me P.E.M. At this point even if i just go to my doctors surgery i'll be ok that night, just tired, but the next day i am extremely ill. Inflammation everywhere, sore brain, eyes, back, legs, arms, nausea, dizziness. Takes me about a week to recover. I believe that my leg muscles are gradually getting worse due to doing this so many times. I said to my doctor that i felt i was doing damage to my leg muscles and that i wasn't going to go to appointments any more without a wheelchair. Also, that it would help about the house if i had something to take the weight off my legs. My GP seemed quite discouraging of this idea, she wanted me to keep using my legs and it didn't sound like she was buying the whole muscle damage thing. She said i need to try and build up muscles slowly. I've never been able to build up my muscles over the 20 years i've had M.E, they have only got gradually weaker. I tried everything, doing it as slowly as possible and never any improvement. Is there any proof i can give my GP that will convince her that resting the muscles is the best way?, cause that's the only thing i've found that has helped. Any studies or trials that prove muscle can't be built up?