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Lessons from ME/CFS: Finding Meaning in the Suffering
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Broad spectrum options for an inflammed gut?

Discussion in 'The Gut: De Meirleir & Maes; H2S; Leaky Gut' started by Kontra, Dec 3, 2012.

  1. Kontra

    Kontra

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    Hi All,

    I'm in pretty bad shape with MCS, liver/methylation issues and a raw, toxic inflammed gut.

    I don't really have a strategy for knowing how to get better but know I somehow need to support my gut. It's quite possible it is the cause of all my issues. I had a metametrix test about a year ago which didn't show much, bar an unidentified parasite and high H pylori. Unfortunately trying mastic gum screwed up my digestion further.

    I can categorise my food sensitivities.....

    Brain fog/autoimmune type reactions - eggs, dairy, nightshades
    weak digestion/constipation/fermentation reactions - fruit, onions (fodmaps), fiber, grains
    blood sugar reactions (hypoglycemia) - rice, high GI veg
    joint pain - sweet potato's
    histamine - fermented foods, wine, cheese etc

    Being very low carb was the only way to avoid all these, but that unfortunately nearly killed me.... Suffered severe electrolyte imbalance, multiple trips to ER, complete lack of appetite, low blood pressure, trouble walking etc.

    In terms of digestive symptoms, which are just a subset of my overall symptoms, I experience

    - Burning bowel movements
    - Sluggish digestion
    - Constipation
    - Left and right abdominal ache
    - Slow stomach emptying
    - Liver/gallbladder ache
    - Foul smelling
    - Undigested food
    - Colour typically heavily based on what was eaten the day before

    Issues with having faith in a protocol

    - Needing carbs but having the digestive issues above.
    - Because I'm very weak, detox reactions are often intolerable. Diarrhea can land me in A&E
    - Because my gut is raw, every bowel movement is uncomfortable
    - Because I'm toxic from MCS/liver dysfunction, detox from this can irritate my gut which might be a necessary evil.
    - Knowing whether to 'soothe' or 'attack'
    - Knowing that one supplement is probably not going to dramatically improve my health due to multiple organ involvement, therefore slowly introducing supplements and monitoring the effect is tricky.

    In terms of what I've tried, I do some relief from digestive supplements, notably enzymes, betaine HCL and pancreatin. Pancreatin has been fairly recent and I can really feel it's working to digest food and also virus's/parasites etc and has helped with my constipation, but it's very potent. I've tried ox bile in the past but it's loosing it's effect.

    Has anyone been in a similar boat and found anything useful as a starting point? I have some single strain acidophilus on order to try which seems like a fairly sensible broad spectrum supplement. I'm then thinking of a biofilm supplement if it's not too rough.

    Many thanks,
    GcMAF Australia likes this.
  2. heapsreal

    heapsreal iherb 10% discount code OPA989,

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    australia (brisbane)
    gut inflammation sacchromyce bouldarri

    Background & Aims:Saccharomyces boulardii is a nonpathogenic yeast used for treatment of diarrhea. We used a mice model of inflammatory bowel disease (IBD) to analyze the effects of S boulardii on inflammation. Methods: Lymphocyte-transferred SCID mice, displaying IBD, were fed daily with S boulardii. Weight loss and inflammatory status of the colon were monitored. Nuclear factor-κB activity was assessed in the colon. The CD4+ T-cell production of interferon (IFN) γ was evaluated by enzyme-linked immunosorbent assay, and a comprehensive reverse-transcription polymerase chain reaction (RT-PCR) analysis for both colon and mesenteric lymph nodes was performed. Finally, we analyzed cell migration mechanisms in vitro and in vivo. Results:S boulardii treatment inhibits IBD. S boulardii induces an accumulation of IFN-γ-producing T-helper 1 cells within the mesenteric lymph nodes correlated with a diminution of CD4+ T-cell number and IFN-γ production by CD4+ T cells within the colon. The influence of S boulardii treatment on cell accumulation in mesenteric lymph nodes was also observed in normal BALB/c mice and involves modifications of lymph node endothelial cell adhesiveness by a yeast secretion product. Conclusions:S boulardii has a unique action on inflammation by a specific alteration of the migratory behavior of T cells, which accumulate in mesenteric lymph nodes. Therefore, S boulardii treatment limits the infiltration of T-helper 1 cells in the inflammed colon and the amplification of inflammation induced by proinflammatory cytokines production. These results suggest that S boulardii administration may have a beneficial effect in the treatment of IBD.
    GcMAF Australia likes this.
  3. SusanB

    SusanB

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    DFW
    I had problems for almost 10 years with diarrhea and rarely constipation, but it was bad enough to require an enema to help move my bowels. It seemed like I had every test in the book, including the mainstream kinds like colonoscopy/endoscopy, stool tests galore, and blood tests. They never could find anything.

    I truly feel for you. It's misery. A friend told me about L.E.A.P and did the blood test to test for food sensitivities. The woman who was certified in L.E.A.P put me on a specialized diet for 6 weeks and then food rotation. The concept is for a very limited diet for 6 weeks n order to take away all of the foods that inflame your gut and give it time to heal. In my case it worked. I had some surprisingly high sensitivities to things like: olives, baker's yeast, coconut, almonds, pistachios, watermelon, tomato, tea, cucumber, maple, and etc. so no more olive oil, maple syrup, almond milk, and so forth! It's funny because foods that were healthy and I was supposed to eat for my health only aggravated my condition. I no longer have diarrhea or constipation.

    I have zero affiliation with LEAP so I'll post the link to the information in case it is helpful: http://www.nowleap.com/index.html The woman who was recommended to me did the test at cost plus a small charge for consultation.
    GcMAF Australia likes this.
  4. FunkOdyssey

    FunkOdyssey Senior Member

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    Ketotifen is developing a reputation for resolving food sensitivities, leaky gut, and irritable bowel syndrome. Independently of all that, if you believe mast cells play a significant role in CFS pathology, ketotifen is the premier systemic and clinically proven mast cell stabilizer.
  5. GcMAF Australia

    GcMAF Australia Senior Member

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    Good points
    Dr lewis finds that 60% of CFS people are intolerant to fructose which is found in fruit, potatoes, carrots sweet potatoes etc and i believe lower in the green leafy vegies (can google this eg http://en.wikipedia.org/wiki/Fructose)
    other high interances are found with glutein and casein
    He finds just eliminating these helps CFS people>
    It is interesting and alarming that we are selecting plant varieties for there sweetness and hence selecting for fruit and vegies that are going to make us sick and possibly die. as indicated by SusanB.
    so maybe a bit more protein?
    there are some books on anti inflammatory diets.
    also maybe inflammation therapy https://chronicillnessrecovery.org/
    maybe have IV drips and allow the gut to recover a bit??
    another thing is that bacteria are associated with the gut problems

    http://www.sciencedaily.com/releases/2010/07/100707141558.htm
    also a lot in the further articles column
    Amid the murk of 'gut flora,' vitamin D receptor emerges as a key player
    www.sciencedaily.comWithin the human digestive tract is a teeming mass of hundreds of types of bacte
    ria, a potpourri of microbes numbering in the trillions that help us digest food and keep bad bacteria in check. Scientists have found that the vitamin D receptor is a key player amid the gut bacteria --

    I hope that this helps
    merylg and heapsreal like this.
  6. AbbyDear

    AbbyDear

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    usa
    Kontra, sorry about the predicament. I can relate, it sounds familiar. I have not found the answer and have no furhter suggestions. Additionally, I have trouble with probiotic, and most fiber (prebiotic).... but without fiber I get so constipated, it is a worse evil. But I feel raw and reactive to most foods. Not sure what to do.

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