The following link will take you to a Dr. Mercola article--one of the best I've run across regarding the correlation between deep sleep and detoxification. There's a couple videos in the article, including a 3-min. segment entitled "The Role of the Glymphatic System in Cleansing the Brain". Lack of Sleep Promotes Alzheimer’s by Preventing Critical Detoxification "By pumping cerebral spinal fluid through your brain's tissues, the glymphatic system flushes the waste from your brain back into your body's circulatory system. From there, the waste eventually reaches your liver, where it's ultimately eliminated. The clincher is that this system ramps up its activity during sleep, thereby allowing your brain to clear out toxins, including harmful proteins called amyloid-beta, the buildup of which has been linked to Alzheimer's. During sleep, the glymphatic system becomes 10 times more active than during wakefulness. Simultaneously, your brain cells shrink by about 60 percent, allowing for greater efficiency of waste removal."