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Brain white matter abnormalities in female interstitial cystitis/bladder pain syndrome: A MAPP Netwo

Discussion in 'Gastrointestinal and Urinary' started by Sherlock, Mar 5, 2015.

  1. Sherlock

    Sherlock tart cherry etc. for joints, insomnia

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    Czechosherlockia, USA
    Just stumbled on this J Urol. 2015 Feb 21 http://www.ncbi.nlm.nih.gov/pubmed/25711200 :
     
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  2. drob31

    drob31 Senior Member

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    I wonder how much the white matter abnormalities have to do with poor circulation. Neuron's require 3 things to stay healthy: glucose, oxygen, and stimulation. I know allot of people have circulation issues, and circulation issues in the hands and feet usually mean there will be circulation issues in the brain in the form of hypoxia. Such the tissues are depleted of oxygen causing neurological issues such as this.
     
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  3. beaker

    beaker ME/cfs 1986

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    I developed IC after alpha interferon treatment. Seems like it could be the cytokines in the CSF/brain that are causing the issue.
     
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  4. drob31

    drob31 Senior Member

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    Indeed, another factor would be a leaky blood brain barrier that allows macrophages entry into the brain to cause havoc.
     
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  5. Kati

    Kati Patient in training

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    NK17 and oceiv like this.

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