1. Patients launch $1.27 million crowdfunding campaign for ME/CFS gut microbiome study.
    Check out the website, Facebook and Twitter. Join in donate and spread the word!
Nitric oxide and its possible implication in ME/CFS (Part 2 of 2)
Andrew Gladman explores the current and historic hypotheses relating to nitric oxide problems in ME/CFS. This second article in a 2-Part series puts nitric oxide under the microscope and explores what it is, what it does and why it is so frequently discussed in the world of ME/CFS....
Discuss the article on the Forums.
  1. Arizona

    Arizona

    Messages:
    34
    Likes:
    6
    I have been on Fred's protocol for a while now. I am taking-

    1 x l-carintine fumerate
    1 x Same
    1 x TMG
    2 x metafolin
    1 x B-complex
    3 x omega 3
    3 x vitamin c
    2 x Zinc
    1 x Calcium/Magnesium
    1 x vitamin A
    1 x vitamin D
    1 x vitamin E
    1 x alpha lipotic acid
    1 x anabol naturals dibencoplex
    1 x potassium
    5 x enzymatic therapy b12 sublingually

    Although I am feeling better I still suffer terribly with brain fog. I was wondering if anyone could give me tips on other things I could try that could help. It's the number one thing I would love to fix. I can't remember the last time I was able to think clearly.
     
  2. Hip

    Hip Senior Member

    Messages:
    3,142
    Likes:
    2,984
  3. Arizona

    Arizona

    Messages:
    34
    Likes:
    6
    Thank you for the suggestion. I will look into it.
     
  4. Star-Anise

    Star-Anise Senior Member

    Messages:
    204
    Likes:
    110
    I found a significant difference between l-carintine and acetyl-l-carnitine. I used this product:
    http://www.nowfoods.com/Sports/Products/Amino-Acids/Acetyl-L-Carnitine-500mg-100-Veg-Capsules.htm
    If the dose between the two forms are not comparable, I would open the capsule & split, because I found the acetyl form to have quite a bit more oomph to it.
    As well, brain fog could be connected to so many things. I'm a big fan of using charcoal as per CBS protocol from Yasko, which assisted me greatly as well. It would hard to be more specific regarding supplements without more information regarding your snps. For example, Tyrosine and phenylalanine were instrumental in helping me take a step out of the fog too. But, this is related to dopamine production, so I would be curious about neurotransmitter function for you in general before making recommendation. Lastly what comes to mind is brain fog could be related to poor gut function too...
    All the best
    S:)
     
  5. Arizona

    Arizona

    Messages:
    34
    Likes:
    6
    Other than brain fog my symptoms include headaches, general muscle tiredness/weaknes, ibs, interstitial cystitis, pain/tremor in both hands and ulcer like symptoms in my stomach for which I sometimes take omeprazole.

    Thank you for the acetyl-l-carnitine suggestion. I will also look into this.
     
  6. maryb

    maryb iherb code TAK122

    Messages:
    2,896
    Likes:
    2,025
    UK
    For someone very sensitive to meds what would you recommend? In so much as is this a high dose? I know you're not a doc hip so its very much on my own decision to try it.
     
  7. GenDylan

    GenDylan

    Messages:
    63
    Likes:
    11
    Choline supplements are very good for brain fog. I'd recommend cdp choline or alpha gpc,because they are less likely to lower dopamine than other choline supps.

    (I've had absolutely constant brain fog for a couple years now)
     
  8. Hip

    Hip Senior Member

    Messages:
    3,142
    Likes:
    2,984
    These choline supplements work well with piracetam, which also works on the cholinergic system. It is generally recommended to take piracetam and choline supplements together.
     
  9. Star-Anise

    Star-Anise Senior Member

    Messages:
    204
    Likes:
    110
    This is what comes to mind when you list your symptoms:
    have you considered magnesium supplements? You will need to be careful as this may aggravate some of your IBS symtoms. My suggestion would be to go reeeeal slow to build bowel tolerance.
    I would explore these two products:
    a) http://www.aor.ca/products-page/classic/magnesium-malate-renew-4/
    b) http://www.metagenics.com/mp/products/mag-glycinate
    I like the mag glycinate product because it is a tablet form and really easy to half or quarter, which is useful when you are starting out. The Malate product, however, many people find useful to address the fatigue element of the muscle weakness as it will tie into the Kreb's Cycle from my understanding.
    These all sound like symptoms that could be related to an inflammatory process that is occurring. Since you are feeling better on Fredd's protocol, this is suggestive that some of the inflammation could be related to chronic undermethylation. However, you may want to consider using products like Curcumin to help calm some of the inflammation down. As well, gut function can be playing a key role in systemic inflammation. The IBS symptoms point this way clearly to me. Have you considered doing a baseline yeast cleanse? I have only had success using this following product:
    http://www.bioticsresearch.com/node/1654
    instead of the usual caprylic acid and/or oregano oil taken orally. I would take this in combination with bentonite and a fibre agent to help move things through, along with my favorite probiotic:
    http://www.natren.com
    I use the dairy-free Biffido powder.
    When I did my first yeast cleanse in this manner, the results were amazing. Probably a good 25% reduction in brain fog.
    You may have to calm some of the inflammation down via products like Curcumin prior to doing cleanse, as it just might be too agitating for your system otherwise.
    All the best,
    Star :)
     
  10. Little Bluestem

    Little Bluestem Senescent on the Illinois prairie, USA

    Messages:
    2,644
    Likes:
    1,993
    Midwest, USA
    What is the 'cdp' in cdp choline and the 'gpc' in alpha gpc?
     
  11. Arizona

    Arizona

    Messages:
    34
    Likes:
    6
    Thank you Star for all your suggestions. I will definitely look into doing the cleanse. At this point I'll try anything to get rid of this brain fog. It is so debilitating and doctors are useless.
     
    Star-Anise likes this.
  12. triffid113

    triffid113 Day of the Square Peg

    Messages:
    702
    Likes:
    224
    Michigan
    Check your thyroid - TSH should be <2.0. See http://www.lef.org/protocols/appendix/blood_testing_02.htm?source=search&key=TSH reference range).
    There are supplements - any good Thorne multile has all the things necessary for your thyroid. If you want a specific supplement tho', then one like this: http://www.iherb.com/Thorne-Research-Thyrocsin-Thyroid-Cofactors-60-Veggie-Caps/21588 - it has the iodine and selenium etc you need. Also as star-anise says, you need tyrosine to make thyroid hormone and if you eat a low protein diet (women usually eat less protein than men due to size anyway) then you may need to supplement it...my doctor put me on 1g/day tyrosine.
     
  13. triffid113

    triffid113 Day of the Square Peg

    Messages:
    702
    Likes:
    224
    Michigan
    Just a suggestion - if bowel problems try magnesium oil. I have it on hand for blood pressure issues "just-in-case" Normally I take calcium citrate + magnesium citrate 1:1 ratio (600mg / day magnesium). If I do not I get arrythmias. I take the citrate fors because citrate prevents kidney stones. Plus my body likes it and does not like other forms (like asporatate). I also tried the malaate and it did nothing for me. From what I had read I was supposed to want the most absorbable form but my body liked citrate so that's what I stick with.
     

See more popular forum discussions.

Share This Page