Does anyone know if anyone is looking into brain or nervous system damage as a cause of our illness? I ask this as I have heard of a few people that have taken DMT and their symptoms completely disappeared for a few hours. I have also heard of a PWCFS take suboxone and it had the same effect. Desperate to feel well I had a very small amount of suboxone and the crushing fatigue completely went away. The next few hours were absolute heaven. My body felt 100% and I was able to do push-ups. This would normally be completely out of the question. I was left with no PEM symptoms. This normally would have left me bed bound for a week. So I wonder if it actually something in the brain that is driving the fatigue symptoms at least. Anyone have any similar experiences, thoughts on this or know of any research into this?