Most studies on gender and ME show that there are more females than males who get the disease. One major difference between the genders are hormones and thereby also how the immune system functions (a immune system with high testosterone is significantly different from one with low testosterone). ME is more or less related to many other syndromes, such as RA. One study have shown that "serum testosterone levels are inversely correlated with RA activity and dehydro-epiandrosterone sulfate (DHEAS) plasma levels are inversely correlated with both disease duration and clinical severity in patients already affected by active RA. (link)". So, I my thoughts where, perhaps a higher level of testosterone would be beneficial for PWME? I am contemplating to begin exercising with weights. The most important reason to not do it for me, is that I am having tendon/inflammation problems around my right elbow. Anyone here who've begun exercising and benefited from it?