The Real ME: A Stock Photography Resource for the Media
We’ve all seen them in the news stories about ME/CFS: the guy in a suit at the office, yawning; the beautiful woman sitting at her desk with her immaculate make-up and elegantly coiffed hair, hand to her head and looking slightly pained.
Discuss the article on the Forums.

"Biomarkers revealed as red herrings are still treated like smoking guns"

Discussion in 'Other Health News and Research' started by Dolphin, Jun 3, 2011.

  1. Dolphin

    Dolphin Senior Member

    Messages:
    9,210
    Likes:
    21,787
    John Ioannidis was one of the authors. He's an interesting researcher in my opinion. He has a degree in mathematics. He often challenges the status quo.

     
  2. Dolphin

    Dolphin Senior Member

    Messages:
    9,210
    Likes:
    21,787
    Abstract

    Here's the abstract - but the other article is easier to read

     
  3. Esther12

    Esther12 Senior Member

    Messages:
    7,345
    Likes:
    20,440
    Thanks.

    Reminds me of the "CFS = Depression" meme which is still going strong amongst doctors, despite the fact that the researchers like Wessely who had promoted it have long since abandoned it. (Isn't there some Wessely quote like: "Whatever's wrong with these patients, it's not depression.")

    It's a pain.
     
  4. Snow Leopard

    Snow Leopard Hibernating

    Messages:
    3,920
    Likes:
    8,446
    South Australia
    Ah, John P. A. Ioannidis of "Why Most Published Research Findings Are False" fame.
    http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.0020124


    "Comparison of Effect Sizes Associated With Biomarkers Reported in Highly Cited Individual Articles and in Subsequent Meta-analyses":
    http://jama.ama-assn.org/content/305/21/2200.short

    The whole scenario of the relative risks being magnitudes of order in the highly cited papers (published in top journals), compared to the subsequent meta-analyses is a clear result of publication/citation biases.
     

See more popular forum discussions.

Share This Page