Can someone explain to me how betablockers work in pots/oi? If one has periods of low blood pressure then my thinking is that it could drop your bp further and one would pass out. I can see how it can help those that get tachycardia and hypertension from it. So would a beta blocker only be used in hypertensive pots/oi or maybe someone with an average bp but gets the tachycardia? I have just watched an interesting utube of a doctor who now uses mainly betablockers as they are the most successful, if they dont work then he moves the patient onto midodrine, which he initially said only seem to help 50% of the patients which was much lower then beta blockers were helping. cheers!!!