For God's sake! Just got this back from Infectolabs. Doctor wants to start me on three months of Trimethoprim and Plaquenil. Borrelia burgdorferi antibodies (immunoblot) Borrelia-Blot-IgG-antibodies + positive Bands: OspC +,p41 +, p83 + Borrelia-Blot-IgM-antibodies negative The specific Borrelia burgdorferi-IgG-antibodies are an indication for a humoral immune response against Borrelia burgdorferi. Borrelia burgdorferi Elispot LTT Borrelia burgd. Fully Antigen + 6 SI < 2 Borrelia OSP-Mix + 4 SI < 2 Borrelia LFA-1 + 7 SI < 2 The results of the Elispot-Lymphocyte-Transformation-Tests are an indication for an actual cellular activity against Borrelia burgdorferi. Results = 2 SI (borderline) or > 2 SI (positive) mean a specific response of the Tlymphocytes regarding the different antigens in the Elispot-LTT. The higher the result of the SI, the stronger is the T-cellular immune-response in general. Also positive for Erlichia and chlamydia pnuemoniae. My DNA PCR test came back negative. I wasn't very interested in having Lyme. Authorities insist Borrelia burgdorferi doesn't exist in my part of the world so i can only think that tick spit has other nasties in it. I got bitten on the belly and the leg about two years before falling ill while working in timber plantations. I was a fence sitter on the Chronic Lyme debate. I really don't like the sound of long term antibiotics, or their success rate. Nor does the CDC and NIH. Now i'm starting to take the stance that as horrible as some of the pharmaceutical treatment sounds, the case studies and post mortems on lyme victims sounds worse! It is one nasty bitch of a bacteria that seems to elude treatment very effectively. Does the CDC's Post infectious lyme autoimmune explanation make more sense? I don't know...but one could die waiting for definitive answers. Should i believe the testing and the doctors verdict?.. Well, i don't know. But i have to make a choice, Yay or Nay very shortly. Sidestepping all the controversy of testing and treatments, my question is... Has anyone else taken Trimethoprim or Plaquenil long term? What sort of side effects can i expect? I am a bit confused as to whether other drugs will be added later. Neither Trimethoprim nor Plaquenil are antibiotics, so maybe they are preliminary treatment for Erlichia and suspected bartonella, babesia, and other antibiotic treatment comes later for Lyme. I will indeed ask before i subject myself to them.