Searching bactrim for sinusitis, seems to be commonly used in the USA but its not used that commonly here in australia. Do people find bactrim helpful for sinusitis when it flares up?? Does it have any more side effects compared with other antibiotics?? I had a recent sinusitis flare after a cold a couple of weeks ago and doxycycline just wasnt cutting the mustard. I have been on augmentin now for 2 days, seems to be doing a good job already. Normally i have been on doxy to prevent sinusitis which has worked well and i stopped taking it at the beginning of the year and was doing ok but i suppose with our dodgy immune systems it just takes a cold to knock us and sinusitis to flare up again. I think the doxy is generally a good preventative but when infection is in full swing we need something abit stronger to hammer the little buggers. it seems like we are always chasing our tails??