Dr. Bateman answers IOM questions from the community: Part 1
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Bacteria 'bricklayer' protein set for attack

Discussion in 'Other Health News and Research' started by Sushi, Jun 20, 2014.

  1. Sushi

    Sushi Moderator and Senior Member Albuquerque

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    http://www.bbc.com/news/science-environment-27907461

     
    rosie26, SOC, Waverunner and 8 others like this.
  2. maryb

    maryb iherb code TAK122

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    @Sushi
    sounds fascinating, it seems to take so long though for these things to get from the science lab into useable drugs:(
     
  3. xchocoholic

    xchocoholic Senior Member

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    Bumping this for others here who're interested in bacteria. It's late and I can't remember who right now. Lol. Tc .. x
     
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  4. xchocoholic

    xchocoholic Senior Member

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    Bumping this once more. X
     
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  5. alex3619

    alex3619 Senior Member

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    This may give us the edge for a few more decades. It wont last though, at least I don't think it can. Picking highly conserved targets is good though ... these are things that cannot change without becoming less optimal.
     
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  6. xchocoholic

    xchocoholic Senior Member

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    Hi @alex3619

    Glad you saw this.

    I thought you may have some thoughts on the
    LptDE protein. They're calling it the bricklayer that pulls up the lipopolysaccharide blocks from inside the bacterium to insert
    Them in the cell wall. That was said about 1/2 way down. Sorry I can't provide the quote.

    I don't understand this but is the cell wall the same as a biofilm ?

    I can't add to these discussions but I enjoy reading them.

    Tx .. x
     
    Last edited: Jun 24, 2014
    rosie26 likes this.
  7. Waverunner

    Waverunner Senior Member

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    "Researchers tell the journal Nature that drugs can now be developed to interfere with this LptDE protein...."

    As maryb has pointed out, that is the problem. It will take 12-15 years till such a drug could get approved but 99% of findings don't get transformed into anything at all. Please notice when scientists end their studies with "could, should, may lead, be used, lay ground to new treatment.". This is desperation and wishful thinking. Scientists somehow hope, that somebody picks up their ideas, spends 800 million to 5 billion dollars and has 12-15 years in order to get a drug approved. This is not the case. What pharma companies prefer to do is use old drugs or mechanisms, improve them, file new patents and sell the new drugs for triple the price. True innovations rare to non-existent.
     

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