Hi all, In the midst of this horrible brain fog, I desperately need to order supplements, especially B12 and Folate, and whatever else would be helpful. I read through Caledonia's guide to SNP interpretation. I had 23 and me done recently, therefore I don't have information on SHMT1. I don't currently have gut issues, but maybe it makes sense to get sulfate strips to check if CBS is an issue? I was planning to order hydroxyB12, and I already have folapro. Or should I consider a combo based on the Yasko protocol? I've been meaning to post my methylation profile for a while, so here it is. I put the major SNPs below. Strange thing: I was on Effexor for a month, and am tapering off now due to horrible side effects. The only good part was that I had way less fatigue and brain fog. Instead I had crippling anxiety. But would this seem to indicate that norepinephrine might be lacking, wouldn't you think? I switched from an SSRI to an SNRI, and am now back on an SSRI. Thanks!!