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B-cell discovery suggests why women suffer more autoimmune disease

Discussion in 'XMRV Research and Replication Studies' started by Deatheye, Aug 5, 2011.

  1. Deatheye

    Deatheye Senior Member

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    http://medicalxpress.com/news/2011-08-b-cell-discovery-women-autoimmune-disease.html

    Not sure if this the right place but since some of the XMRV talk is about B cells I thought I put it in here.
  2. heapsreal

    heapsreal iherb 10% discount code OPA989,

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    australia (brisbane)
  3. Enid

    Enid Senior Member

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    Thank you both - very interesting indeed - herpes viruses high profile now.
  4. redo

    redo Senior Member

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    The B cell depleting agent Rituximab have worked on both MS and RA in some studies, so I think it makes sense.
  5. redo

    redo Senior Member

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    If indeed the B cells are what's causing problems in RA and MS, I guess the natural question is: What makes the B cells act funny. I am guessing a virus has "camped" inside them...
  6. aprilk1869

    aprilk1869 Senior Member

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    Scotland, UK
    Some time ago I got the free booklet on probiotics from iherb. In the booklet it says:-

  7. In Vitro Infidelium

    In Vitro Infidelium Guest

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    Abstract http://bloodjournal.hematologylibra...ract?sid=101a7e37-da8e-4049-a4de-85a13cbed3f9

    This is a mouse study with only a tenuous linkage to humans "We were able to detect a similar population of B cells in the peripheral blood of some elderly women with autoimmune disease, suggesting that there may be parallels between the creation of ABC-like cells between mice and humans."

    IVI
  8. Snow Leopard

    Snow Leopard Senior Member

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    There are already quite a number of studies linking B-cell autoimmune activity to certain diseases, so this sort of finding is not unexpected.

    IVI - I guess that is why the title is "suggests" and not "shows" or "proves"...
  9. fla

    fla Senior Member

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    Montreal, Canada
    Any study aimed at improving understanding the the underlying mechanisms of auto-immunity are welcome. The NCF's (National CFIDS Foundation) working hypothesis has been that M.E. is an auto-immune condition since 2009 Hokama et al found a 95% hit rate in M.E. patients.

    Note this is a human study with only tenuous linkage to mice.
  10. Jemal

    Jemal Senior Member

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    Why do I have the feeling this auto-immunity is caused by the immune system targeting viruses, though (viruses we might not be able to detect at the moment)? So many young acquaintances are falling ill with auto-immune disorders (MS, Wegener's granulomatosis, etc), it ain't funny anymore...

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