Invest in ME Conference 12: First Class in Every Way
OverTheHills wraps up our series of articles on this year's 12th Invest in ME International Conference (IIMEC12) in London with some reflections on her experience as a patient attending the conference for the first time.
Discuss the article on the Forums.

B Cell Depletion treatments

Discussion in 'General ME/CFS Discussion' started by digital dog, Nov 6, 2015.

  1. digital dog

    digital dog Senior Member

    Messages:
    608
    Likes:
    935
    Are there any other B cell depletion treatments other than rituximab that are more widely available in the UK?
    Are there any other treatments that work similarly?
     
  2. digital dog

    digital dog Senior Member

    Messages:
    608
    Likes:
    935
    Please forgive my ignorance but is Rituximab licensed in the UK for RA? My father and other family members have RA but this treatment has never been suggested.
     
  3. helen1

    helen1 Senior Member

    Messages:
    974
    Likes:
    1,371
    Canada
    @digital dog

    Cyclophosphamide, a chemo drug is mentioned a few times on various threads as being similar to rituximab. Don't know if it's more available in the UK. Apparently, it has a faster onset of effect.
     
  4. Scarecrow

    Scarecrow Revolting Peasant

    Messages:
    1,903
    Likes:
    5,385
    Scotland
    It is, but not used automatically. This is from the Arthritis Research UK website:

    http://www.arthritisresearchuk.org/arthritis-information/drugs/rituximab/why-is-it-prescribed.aspx

     
  5. digital dog

    digital dog Senior Member

    Messages:
    608
    Likes:
    935
    Thank you for taking the time to post. I appreciate the replies.
     
  6. gregh286

    gregh286 Senior Member

    Messages:
    636
    Likes:
    909
    Londonderry, Northern Ireland.
    Rituximab is last chance saloon drug in uk for severe cases of RA.
    I think we can improve ourselves without it.
     
  7. Jonathan Edwards

    Jonathan Edwards "Gibberish"

    Messages:
    5,250
    Likes:
    32,008
    Er, not quite. It is one a several very effective treatments. It comes about half way down the list purely for historical licensing reasons - TNF inhibitors were licensed first so have to be tried first. Rituximab is good treatment for mild progressive RA. It is the biologic drug of choice in countries where TB is common, as in much of Latin America.
     
    MEMum, gregh286 and Battery Muncher like this.
  8. msf

    msf Senior Member

    Messages:
    3,204
    Likes:
    4,499
    That licensing thing is crazy - do they do that in other countries too?
     
  9. Jonathan Edwards

    Jonathan Edwards "Gibberish"

    Messages:
    5,250
    Likes:
    32,008
    Less so I think, except maybe in countries more English than England - like New Zealand!
     
    MEMum and Battery Muncher like this.

See more popular forum discussions.

Share This Page