Review: 'Through the Shadowlands’ describes Julie Rehmeyer's ME/CFS Odyssey
I should note at the outset that this review is based on an audio version of the galleys and the epilogue from the finished work. Julie Rehmeyer sent me the final version as a PDF, but for some reason my text to voice software (Kurzweil) had issues with it. I understand that it is...
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B Cell Depletion treatments

Discussion in 'General ME/CFS Discussion' started by digital dog, Nov 6, 2015.

  1. digital dog

    digital dog Senior Member

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    Are there any other B cell depletion treatments other than rituximab that are more widely available in the UK?
    Are there any other treatments that work similarly?
     
  2. digital dog

    digital dog Senior Member

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    Please forgive my ignorance but is Rituximab licensed in the UK for RA? My father and other family members have RA but this treatment has never been suggested.
     
  3. helen1

    helen1 Senior Member

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    @digital dog

    Cyclophosphamide, a chemo drug is mentioned a few times on various threads as being similar to rituximab. Don't know if it's more available in the UK. Apparently, it has a faster onset of effect.
     
  4. Scarecrow

    Scarecrow Annie Gsampel

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    It is, but not used automatically. This is from the Arthritis Research UK website:

    http://www.arthritisresearchuk.org/arthritis-information/drugs/rituximab/why-is-it-prescribed.aspx

     
  5. digital dog

    digital dog Senior Member

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    Thank you for taking the time to post. I appreciate the replies.
     
  6. gregh286

    gregh286 Senior Member

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    Londonderry, Northern Ireland.
    Rituximab is last chance saloon drug in uk for severe cases of RA.
    I think we can improve ourselves without it.
     
  7. Jonathan Edwards

    Jonathan Edwards Senior Member

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    Er, not quite. It is one a several very effective treatments. It comes about half way down the list purely for historical licensing reasons - TNF inhibitors were licensed first so have to be tried first. Rituximab is good treatment for mild progressive RA. It is the biologic drug of choice in countries where TB is common, as in much of Latin America.
     
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  8. msf

    msf Senior Member

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    That licensing thing is crazy - do they do that in other countries too?
     
  9. Jonathan Edwards

    Jonathan Edwards Senior Member

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    Less so I think, except maybe in countries more English than England - like New Zealand!
     
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