Hi Joseph, I'm very glad this information has helped. I put it together but mostly employed data mining to find out what worked for people with my symptoms, avoiding "belief systems", hypotheses and theories and going for actual results. Fortunately many other people are getting similar results. Finding out how terribly important BRAND and/or variety of mb12 is and avoiding light during mixing and use of injectable products makes it a challenge to get repeatable and predictable results. I also read research with a jaundiced eye for false or unjustifiable assumptions, weasel words and outright dumb mistakes. I found that it took about 9 months for many of the things to change, especially neurologically and that each time I added certain additional cofactors I would start a new 9 month period of turbulence ending in more neurological healing. I don't know exactly what you have been doing or your timing or how long your system takes to heal various things. I have had some degree of improvement neurologically continuing on and off for almost 8 years. So good luck and keep on going. They one thing that set me back 2 years neurologically was 6 weeks of glutathione (precursors) including MAXGL.