Hi Jerry, When you were taking the mb12 did you see any improvments in the first few months to keep yourself going? The problem I have got is I dont seems to show any improvments whilst I am on it, it is just as hard if not worse 2 months in. The second month I was floundering around and going rapidly backwards as the brand we were trying that month since the stores and internet vedors were all out of the brand I had tried first that worked great didn't work at all and other brand barely was active. By the time we had located another 5 star brand an entire month passed by. Then I had several mnoths of startup starting over about 90%. So I'll tell you what ocurred when by months of use, not including the backwards month. First 15 minutes - Energy starts flowing. My brain starts to turn on. Awareness changes. Mood starts changing. Things start to brighten. With the first tablet by 15 minutes I was glued in my chair with the intensity (without object, just intensity). Bone crushing fatigue starts lifting. First hour - bone crushing total fatigue present for 16 years starts lifting in 15 minutes and is much gone in 1 hour. The "lights came on", quite literally. Everything brightened viusually about 2 stops (4x) suddenly. A lifelong depression started lifting at 15 minutes and was largely gone in 1 hour. Every pain in my body shines out in full detail. Light headed and a little dizzy describe it. But not the dizziness that put me on the floor when the deficiency hit hard. First day - Lactic acid burn in muscles starts diminishing. Burning tongue comes off the hard burn edge. Bladder comes off hard burn edge. First 10 days - Lactic acid burning pain in muscles completely gone. Burning bladder, burning urethra, burning "urgency", beef-red burning tongue almost completely gone. Sense of smell changes/improves dramatically. Sense of taste changes/improves dramaitically. Sense of hearing sharpens. Abbility to focus eyes comes back. Also, my body is stepping backwards through hundreds of symtoms as each one reverts step by step to earlier versions. Going in these steps were hardly noticable becasue they were spread out over 55 years. Coming out of it things are changing almost daily. First 9 months - Sense of touch in skin changes from painful to normal. Most neuropathies gone. Control over bladder is fully returned. Most peripheral neupathies are getting better. Burning neurological pain is gone, Dilantin discontinued. Sleep restored to normal, provigil discontinued. Muscle spasms decrease 95%, valium & lorazapam are tapered. Asthma symptoms go away. Albuterol discontinued. Nausea and IBS are gone. Compazine suppositorties discontinued. I realized that what ever was missing and keeping me from feeling "happy" was no longer missing and that I could feel happy again. It was quite sudden. Following adb12, rest of muscle pain goes away. Muscles start growing with exercise. Overall pain had decreased 95%, morphine daily dose reduced 40%. I can now walk down the detergent aisle without an asthma attack. Exercise tolerance is back. I get tired at night insread of exhausted all the time. I experience more frequent palpitations / arrythmias I had these for years during deficiencies. It finally took an additional 50mg of zinc and B-RIGHT twice a day as some of the b compnents are short halflife. It turned out to be also cofactor related however arrythmias are a frequent b12 deficiency symptom. The dizziness usually comes on within 15 minutes of taking the mb12 sublingual and lasts for 2 days even if I dont take any more. Now that is interesting. That first 15 minutes is very suggestive. That limits it to a relatively small amount of mb12 required as it is just beginning to get into serum. It limits it to things that can happen quickly. These are also the things that start fading after generally a few months or when an equilibrium level is reached so that each days dose doesn't push the serum level up significantly or increase the level in mitochnodria. The lower the dose the longer this period lasts. At some low level of dosage this appears to go on indefinitely as the body loses as much each day as is taken in and the change induced by the dose is significant compared to what is already there. I finally got tired of this and experimented by increasing the dosage. I just did one after another. Each tablet had less effect than the previous. After a couple of days of doing 50-60mg each day the effects of the tablets faded away in a few days after month after month of no real change. I am just finding it difficult to accept that I have to go so badly backwards to go forwards and am concerned I might just be hindering myself. No matter how intensified or scrambed up the symptoms got I never assumed I was going backwards. At times I was going literally backwards as the symptoms worked backwards through the progressions they had made getting there. This was healing, not going backwards unless you consider it backing up through the symptoms to get to the point before symptoms. I don't believe that you are hindering yourself. However you have to decide for yourself. I have walked this way and recognize the landmarks. As far as I can tell you are just describing it differently that I did. You may have to experience every symptom you have expeienced in the last 30 years getting to now including some you don't remember or didn't notice on the way in. Good luck.