Jaz; Hi Jaz, Honestly, I feel better too when I can help someone else, even in the smallest way! It seems to me that you are responding to the jarrow's. Even though it's weaker, it still has some potency. When nerves are healing, there can be some uncomfortable tingles and zings. It can take some months for the tingles to stop. The areas become smaller, then smaller, and less intense, less often. The muscle spasms may be from the need for more potassium. Unfortunately, the fatigue can be slow to leave. ( As I recall, it took at least 3-4 months to begin to go.) Freddd encouraged people to combine Enzymatic Therapy with Jarrow in the past. He wrote that there was some sort of synergy. He now only recommends ET. He's looking for other effective brands. I don't remember very well, but I think it's recommended to take the sublinguals with an empty stomach. ( I usually do.) Since only a certain amount can be absorbed by the body at one time, it may be better, more economical, to take it in divided doses, such as several times each day. Regarding your question about finding one's personal dosage amount....I've found this to be very difficult. In the beginning, one may need alot more for a time. ( loading doses) Then after a time, ( 1-3 months, I guess), one could reduce the dosage and find a maintenance dose. I've been having this problem lately. I've recently lowered my dosage because I finally began to feel over-methylated. ( I'm still working on this, some of the effects were from having too many methyl donors. Some people need more than others; this is one complicated process.) Sorry that the paresthesias have spread, but now you've got the remedy, MB12. If you feel you need higher dosages, the AOR brand comes in 5mg. and 15mg. sublinguals. My best to you!