Thanks, Freddd. Oops! I was at about ten times the dose I should have been yesterday, then. I've had another 2 tabs today of adB12 so I expect I'm pretty topped up with it for now and will leave it alone for a week. I'll start with mB12 tomorrow morning. I've been feeling surprisingly gloomy the last few days, especially considering that I was able to do a bit more than usual, so maybe that was brought on by too much adB12 without any mB12 to balance. Thank you very much indeed for your replies - it's quite a complex process and quite hard to tackle with brainfog on top!