Hi Ukme, It was not one of the ones tested. Further because it contains mgs of cyanocbl and hydroxycbl I wouldn't touch it with a 10 foot pole. As most brands tested were very inferior compared to the two most effective brands the odds are that it isn't very effective. As the most effective brands of mb12 were 100 times more effective or more than the least effective brands, and perhaps 20 times more effective than the average brands tested It also makes any questions you ask about "why isn't my program effective?" come back to "Are you using the 5 star brands of mb12 and adb12?" If you are using the 5 star brands then we can can proceed to pin down what the other problems are. It's the same thing with folic/folinic acid now. If you are taking one or both of those they become the most likely place to look for problems. The other thing is, since cyanocbl and/or hydroxycbl have to be converted first to the active forms to be any use at all, and these convert at best some 10s of mcg per day they are nopt going to add much of anything to the effectiveness and yet they cost a lot of the price. Further Hydroxycbl causes acne type lesions (what about other lesions we can't see so easily?) in some people which is clearly cell reproduction not working correctly, and it is only effective on about 1/3 of the active b12 deficiency symptoms for about 2/3 of people, over all effectiveness about 2/9 (about 22%) doesn't sound like a good buy to me. This looks like a product designed by marketing people who just don't look very deeply into what they are doing or why. So if you get established on the 5 star mb12 and adb12 and Metafolin and the other cofactors, and everything is going well, then try the Prohealth extreme you will be able to find out how well it does or doesn't work. You need a basis of comparison or you will never know.