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Azathioprine

Discussion in 'Antivirals, Antibiotics and Immune Modulators' started by Sidney, May 31, 2015.

  1. Sidney

    Sidney Senior Member

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    SF Bay Area, USA
    Does anyone have any experience of Azathioprine? ('Imuran' in non-generic - in U.S., at least).

    I have just begun it, substituted for Plaquenil, which was working very very slowly, if at all, by my rheumatologist. It is for my main symptom, profound fatigue (PEM etc), with Sjogren's, and PMR, now under control.
    I felt horrible, sick headache, etc., just for a few hours, about 5 hours after each dose.
    I'm inclined to return to Plaquenil, which at least had no noticeable side effects!

    Apologies if this is already a thread - I couldn't find it.
    Thanks for any input!
     
  2. greeneagledown

    greeneagledown Senior Member

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    Hi, @Sidney. What ever happened? Did you come off Imuran? Has it caused any of your symptoms to become permanently worse? I ask because I just got put on it for Crohn's.
     
  3. Sidney

    Sidney Senior Member

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    SF Bay Area, USA
    I am so sorry, I can't help much, because I just stopped it immediately and went back Plaquenil, which at least had no bad side effects! I am so sorry about your Crohn's, good luck.
     
  4. JES

    JES Senior Member

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    Imuran is a strong immunosuppressant and among other side effects increases cancer risk. My advice is not a doctor's advice, but I would try with immune suppressants/modulators like Wellbutrin and LDN first for something like Crohn's disease, as their side effect profile and safety is excellent compared to drugs like Imuran.
     

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