If you are suffering from anxiety, you might be interested in the supplements details on the following thread: Completely eliminated my severe anxiety symptoms with three supplements! | Phoenix Rising ME / CFS Forums My generalized anxiety disorder was moderate to severe, but these supplements, especially NAG, eliminated it. Lots of other people have tried the same protocol, and around half of them reported very good results like I had, but the other half don't seem to get any benefit at all. Holistic approaches sound good in principle, but it may just mean that the practitioners don't actually know which parts of their therapy work and which are just incidental, so they just give you everything in the hope that some of the treatments will have a positive effect. I think it is important to figure out the key treatments without which the benefits will not manifest, and which are the incidental treatments which may help, but are not essential. That said, I did try out the shirodhara treatment last night in my bath. (I just filled a 5 liter plastic container with warm water, and used some thin plastic tubing I had to make a syphon, such that the water flowed slowly and gently out onto my forehead while I was lying in the bath; it took about 10 minutes for the whole 5 liters to slowly empty on my forehead). It did create a relaxing effect reminiscent of meditation; however, I felt that the effect was unfortunately mostly lost in my ME/CFS "wired but tired" and brain fogged mental state. The calm yet perceptive mind that mindfulness meditation (and no doubt shirodhara) brings tend to be countered by the "wired" and blurred imperceptive condition of ME/CFS. But I will try again in my bath today.