Home care is the theme for Severe ME Day on August 8th
Why should home care be the theme on Understanding and Remembrance Day for Severe ME on August 8? Helen Brownlie of the 25% ME Group has written an explanation for Phoenix Rising ...
Discuss the article on the Forums.

Autoimmunity Question

Discussion in 'Immunological' started by PhoenixBurger, May 5, 2013.

  1. PhoenixBurger

    PhoenixBurger Senior Member

    Messages:
    200
    Likes:
    170
    This is a general question on autoimmunity.

    Is it common for a person with an autoimmune disorder developing, to show "positive" for antibodies to diseases that are not currently present, but were in the past?

    There is a syndrome called IRIS where this happens, but its a very strange phenomenon. People who once had CMV may show positive IGG (acute) infection antibodies even when no acute infection is happening. Same goes for other already-resolved infections from their past. The key is that they always test negative on the actual PCR looking for viral replication. There is none.

    When someone has autoimmunity developing, in general, is this a common thing to see? Positive antibody tests to things but negative PCR's? Or does this seem to be fairly rare and not usually associated with traditional autoimmune disease...

    Thanks
     
  2. Legendrew

    Legendrew Content team

    Messages:
    540
    Likes:
    728
    UK
    I have heard of diseases where you get large clonal expansion of a wide variety of antibodies so I guess it's possible
     

See more popular forum discussions.

Share This Page