As I have only had a short crash course in AAG since KangaSue mentioned it to me a couple of weeks ago, I hope someone may be able to shed some light onto the following!
While reading the AGIDE website particularly the Autoimmune Dysautonomia page there is a list of various tests on offer. Some of these tests are related to Anti Nuclear Neuronal Antibodies (ANNA's) - such as ANN1S, ANN2S and ANN3S.
Now in my limited research of this topic, ANNA's are not talked about very much, so let me quote something which was on a test I had done in 2008 and again last month - 2016. Most of the tests done at that time (soon after I became quite ill in 2007) were negative, including as I have said before, the ANA's and the Sjögrens SSA/SSB specific antibodies. However something which has always piqued my curiosity was my ANCA's (Anti-Neutrophil Cytoplasmic Antibodies) which were done and I quote from the report:
"ANCA - Unable to determine the presence of ANCA because of the presence of anti-neutrophil nuclear antibodies (ANNA's). Please see the result for Myeloperoxidase-ANCA (major P-ANCA) and Proteinase 3-ANCA (major C-ANCA antigen).”
The Myeloperoxidase and the Proteinase ANCA's were both in range at <5 U/mL. (RR <5)
The latest ANCA done last month - Feb 2016 reported:
"ANCA (11F) Result: Weakly Positive and Pattern: Atypical".
Three questions:
1). has anybody had this type of comment relating to ANNA's on their ANCA reports.
2). could this veiled ANCA result have anything to do with the ANN1S, ANN2S & ANN3S which are mentioned on the AGIDE Dysautonomia webpage?
3). something else altogether?
I hope I have communicated clearly enough what has been puzzling me for a long time!
Megan
While reading the AGIDE website particularly the Autoimmune Dysautonomia page there is a list of various tests on offer. Some of these tests are related to Anti Nuclear Neuronal Antibodies (ANNA's) - such as ANN1S, ANN2S and ANN3S.
Now in my limited research of this topic, ANNA's are not talked about very much, so let me quote something which was on a test I had done in 2008 and again last month - 2016. Most of the tests done at that time (soon after I became quite ill in 2007) were negative, including as I have said before, the ANA's and the Sjögrens SSA/SSB specific antibodies. However something which has always piqued my curiosity was my ANCA's (Anti-Neutrophil Cytoplasmic Antibodies) which were done and I quote from the report:
"ANCA - Unable to determine the presence of ANCA because of the presence of anti-neutrophil nuclear antibodies (ANNA's). Please see the result for Myeloperoxidase-ANCA (major P-ANCA) and Proteinase 3-ANCA (major C-ANCA antigen).”
The Myeloperoxidase and the Proteinase ANCA's were both in range at <5 U/mL. (RR <5)
The latest ANCA done last month - Feb 2016 reported:
"ANCA (11F) Result: Weakly Positive and Pattern: Atypical".
Three questions:
1). has anybody had this type of comment relating to ANNA's on their ANCA reports.
2). could this veiled ANCA result have anything to do with the ANN1S, ANN2S & ANN3S which are mentioned on the AGIDE Dysautonomia webpage?
3). something else altogether?
I hope I have communicated clearly enough what has been puzzling me for a long time!
Megan
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